Author

L. A. Leaton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Research Focus:variant calling· 1

Frequent Co-Authors

P. J. Norman· 2 shared A. Campos Codo· 1 shared A. Getahun· 1 shared A. van Bokhoven· 1 shared B. A. Lie· 1 shared B. Crute· 1 shared C. R. Gignoux· 1 shared D. Vukcevic· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

P. J. Norman

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Author profile →

2 papers

Recent·Most cited

Polymorphic KIR3DL3 expression modulates tissue-resident and innate-like T cells.

W. H. Palmer, L. A. Leaton, A. Campos Codo, P. S. Hume, B. Crute, M. Stone, A. van Bokhoven, R. P. Tobin, M. McCarter, W. J. Janssen, J. Roest, S. Zhu, J. Petersen, J. P. Vivian, J. Rossjohn, , P. J. Norman

This study identifies KIR3DL3 expression in T cells, showing it is upregulated by unconventional stimulation and varies by individual genetic variants.

bioRxiv · Aug 17, 2022Immunology

Allele imputation for the Killer cell Immunoglobulin-like Receptor KIR3DL1/S1

G. F. Harrison, L. A. Leaton, E. A. Harrison, M. K. Viken, J. Shortt, C. R. Gignoux, B. A. Lie, D. Vukcevic, S. Leslie, P. J. Norman

This paper develops PONG, a method to impute KIR3DL1/S1 alleles from whole-genome SNP data with high accuracy across populations, enabling large-scale genetic studies.

PLOS Computational Biology · Feb 22, 2022Peer-reviewedImmunology