L. A. Robinson

Adenomatous polyposis coli (APC) regulates internalization and signaling of the chemorepellent receptor, Roundabout (ROBO) 1

This study identifies APC's role in SLIT2-induced ROBO1 endocytosis and its impact on cell morphology.

The tumor microbiome reacts to hypoxia and can influence response to radiation treatment in colorectal cancer

The paper examines how hypoxia affects the tumor microbiome and its interaction with radiation response in colorectal cancer using RNA-seq data and experimental models.

The tumor microbiome as a predictor of outcomes in patients with metastatic melanoma treated with immune checkpoint inhibitors

This study identifies microbes associated with immunotherapy response in metastatic melanoma and shows that combining microbe abundances with gene expression improves survival prediction.

The chemorepellent, SLIT2, bolsters innate immunity against Staphylococcus aureus

SLIT2, a neuro-repellent, enhances neutrophil antibacterial activity against S. aureus by boosting reactive oxygen species production and granule exocytosis, improving infection clearance.

Endothelial integration of mechanosensory signals by the spectrin cytoskeleton

This study shows that the spectrin cytoskeleton in endothelial cells is essential for sensing and transmitting shear stress to mechanosensors, leading to vasoactive responses.