Author

L. Bischof

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:imaging· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

B. Fabry· 3 shared C. Mark· 3 shared R. Gerum· 3 shared S. Budday· 3 shared A. Bauer· 2 shared C. Voskens· 2 shared D. Boehringer· 2 shared R. Strick· 2 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersBiophysics

B. Fabry

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Fiber alignment in 3D collagen networks as a biophysical marker for cell contractility

D. Boehringer, A. Bauer, I. Moravec, L. Bischof, D. Kah, C. Mark, T. J. Grundy, E. Goerlach, G. M. O'Neill, S. Budday, P. Strissel, R. Strick, A. Malandrino, R. Gerum, M. Mak, , B. Fabry

This study uses fiber alignment and density in 3D collagen networks as a proxy for cell traction forces, validated in hepatic stellate cells and glioblastoma cell lines, and provides an open-source tool for drug screening.

bioRxiv · Jun 28, 2023Biophysics

Immune cells employ intermittent integrin-mediated traction forces for 3D migration

T. Czerwinski, L. Bischof, D. Böhringer, S. Kara, P. L. Strissel, R. Strick, A. Winterl, R. Gerum, E. Wittmann, M. Schneider, M. W. Beckmann, G. Nusser, M. Wiesinger, S. Budday, A. Lux, , C. Mark

This study shows immune cells switch between amoeboid and contractile migration modes in dense matrices, using integrin-mediated forces to navigate steric hindrance.

bioRxiv · Apr 20, 2023Biophysics

Dynamic traction force measurements of migrating immune cells in 3D matrices

D. Boehringer, M. Condor, L. Bischof, T. Czerwinski, N. Gampl, P. A. Ngo, A. Bauer, R. Lopez-Posadas, K. Franze, C. Voskens, S. Budday, C. Mark, B. Fabry, R. Gerum

This study measures dynamic traction forces of migrating NK cells in 3D matrices and finds that force bursts increase with matrix stiffness to aid migration through constrictions.

bioRxiv · Nov 16, 2022Biophysics