B. Fabry

Contractility of cardiac and skeletal muscle tissue increases with environmental stiffness

This study shows that contractile force in cardiac and skeletal muscle tissues increases with environmental stiffness following a power-law relationship.

Remote sensing of emperor penguin abundance and breeding success

This paper develops a phenological model to predict emperor penguin breeding pairs and chicks from sparse satellite data, improving population monitoring in remote areas.

Fiber alignment in 3D collagen networks as a biophysical marker for cell contractility

This study uses fiber alignment and density in 3D collagen networks as a proxy for cell traction forces, validated in hepatic stellate cells and glioblastoma cell lines, and provides an open-source tool for drug screening.

Direct 3D-bioprinting of hiPSC-derived cardiomyocytes to generate functional cardiac tissues

This paper describes a method to directly 3D-bioprint hiPSC-derived cardiomyocytes into functional cardiac tissues that contract and respond to pharmacological stimulation.

Immune cells employ intermittent integrin-mediated traction forces for 3D migration

This study shows immune cells switch between amoeboid and contractile migration modes in dense matrices, using integrin-mediated forces to navigate steric hindrance.

Clinorotation inhibits myotube formation by fluid motion, not by simulated microgravity

This study shows that clinorotation inhibits myotube formation due to fluid motion, not simulated microgravity, and recommends control experiments to distinguish these effects.

Dynamic traction force measurements of migrating immune cells in 3D matrices

This study measures dynamic traction forces of migrating NK cells in 3D matrices and finds that force bursts increase with matrix stiffness to aid migration through constrictions.

Predicting cell stress and strain during extrusion bioprinting

The paper predicts cell stress and strain during extrusion bioprinting using simulations and develops methods based on printing parameters.

Dual-wavelength stopped-flow analysis of the lateral and longitudinal assembly kinetics of vimentin

This paper measures vimentin filament assembly kinetics using dual-wavelength stopped-flow light scattering, showing both lateral and longitudinal assembly rates increase with salt concentration.

Viscoelastic properties of suspended cells measured with shear flow deformation cytometry

This paper introduces a microfluidic method to measure viscoelastic properties of suspended cells using shear flow deformation cytometry and demonstrates cell cycle-dependent rheological behavior.

The desmin mutation R349P increases contractility and fragility of stem cell-generated muscle micro-tissues

This study shows that the desmin mutation R349P increases contractility and fragility of muscle micro-tissues generated from stem cells, leading to rapid disintegration and mechanical rupture.

Stress relaxation amplitude of hydrogels determines migration, proliferation, and morphology of cells in 3-D

This study shows that the stress relaxation amplitude of hydrogels affects cell migration, proliferation, and morphology more than the relaxation time constant.

Biologging of emperor penguins - attachment techniques and associated deployment performance

This paper evaluates biologging techniques for emperor penguins, finding that traditional gluing methods harm birds and proposing alternative attachment methods with better deployment success.

Juvenile emperor penguin range calls for extended conservation measures in the Southern Ocean

The paper shows that juvenile emperor penguins spend most of their time outside current marine protected areas, highlighting the need for expanded conservation measures.

pyTFM: A tool for Traction Force and Monolayer Stress Microscopy

pyTFM is a tool for Traction Force and Monolayer Stress Microscopy that enables non-expert users to analyze cell-matrix tractions and stresses using synthetic and experimental data.

High-force magnetic tweezers with hysteresis-free force feedback

This paper introduces a method to eliminate magnetic hysteresis in magnetic tweezers using force feedback, enabling precise force control and new insights into cell mechanics.

Cryopreservation impairs cytotoxicity and migration of NK cells in 3-D tissue: Implications for cancer immunotherapy

This study shows that cryopreservation reduces NK cell cytotoxicity and motility in 3-D collagen gels, potentially explaining the failure of NK cell therapies for solid tumors.

Measurement of skeletal muscle fiber contractility with high-speed traction microscopy

This paper introduces a method to measure contractile forces and calcium dynamics in single muscle fibers using high-speed traction microscopy and applies it to mouse fibers.

Collective forces of tumor spheroids in three-dimensional biopolymer networks

This study quantifies collective contractile forces of tumor spheroids on 3D collagen networks, showing initial cell-level contractility and later matrix-guided forces.