Author

T. Czerwinski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:flow cytometry· 1 Organism:mouse· 1

Frequent Co-Authors

B. Fabry· 3 shared C. Mark· 3 shared A. Winterl· 2 shared C. Voskens· 2 shared L. Bischof· 2 shared R. Gerum· 2 shared S. Budday· 2 shared A. Bauer· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersBiophysics

B. Fabry

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Immune cells employ intermittent integrin-mediated traction forces for 3D migration

T. Czerwinski, L. Bischof, D. Böhringer, S. Kara, P. L. Strissel, R. Strick, A. Winterl, R. Gerum, E. Wittmann, M. Schneider, M. W. Beckmann, G. Nusser, M. Wiesinger, S. Budday, A. Lux, , C. Mark

This study shows immune cells switch between amoeboid and contractile migration modes in dense matrices, using integrin-mediated forces to navigate steric hindrance.

bioRxiv · Apr 20, 2023Biophysics

Dynamic traction force measurements of migrating immune cells in 3D matrices

D. Boehringer, M. Condor, L. Bischof, T. Czerwinski, N. Gampl, P. A. Ngo, A. Bauer, R. Lopez-Posadas, K. Franze, C. Voskens, S. Budday, C. Mark, B. Fabry, R. Gerum

This study measures dynamic traction forces of migrating NK cells in 3D matrices and finds that force bursts increase with matrix stiffness to aid migration through constrictions.

bioRxiv · Nov 16, 2022Biophysics

Cryopreservation impairs cytotoxicity and migration of NK cells in 3-D tissue: Implications for cancer immunotherapy

C. Mark, T. Czerwinski, S. Roessner, A. Mainka, F. Hörsch, L. Heublein, A. Winterl, S. Sanokowski, S. Richter, N. Bauer, G. Schuler, B. Fabry, C. J. Voskens

This study shows that cryopreservation reduces NK cell cytotoxicity and motility in 3-D collagen gels, potentially explaining the failure of NK cell therapies for solid tumors.

bioRxiv · Oct 21, 2019 · PreprintImmunology