Author

J. C. Benson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:mechanistic / dynamical model· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

M. Trebak· 3 shared N. Hempel· 3 shared A. E. Abdelnaby· 2 shared M. T. Johnson· 2 shared P. Xin· 2 shared T. Pathak· 2 shared V. Walter· 2 shared A. T. Elhaw· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersCancer Biology

M. Trebak

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Loss of STIM2 in colorectal cancer drives growth and metastasis through metabolic reprogramming and PERK-ATF4 endoplasmic reticulum stress pathway

T. Pathak, J. C. Benson, M. T. Johnson, P. Xin, A. E. Abdelnaby, V. Walter, W. A. Kultun, G. S. Yochum, N. Hempel, M. Trebak

This study shows that loss of STIM2 in colorectal cancer promotes tumor growth and metastasis through metabolic reprogramming and activation of the PERK-ATF4 ER stress pathway.

bioRxiv · Oct 2, 2023 · PreprintCancer Biology

Alternative splice variants of the mitochondrial fission protein DNM1L/Drp1 regulate mitochondrial dynamics and cell fate in ovarian cancer.

Z. Javed, D. H. Shin, W. Pan, S. R. White, Y. S. Kim, A. T. Elhaw, S. Kamlapurkar, Y.-Y. Cheng, J. C. Benson, A. E. Abdelnaby, R. Phaeton, H.-G. Wang, S. Yang, M. L. G. Sullivan, C. St. Croix, , N. Hempel

This study identifies an alternative splice variant of Drp1 in ovarian cancer that promotes metastasis and chemoresistance by altering mitochondrial dynamics.

bioRxiv · Sep 20, 2023Cancer Biology

Regulation of Interorganellar Ca2+ Transfer and NFAT Activation by the Mitochondrial Ca2+ Uniporter

R. E. Yoast, S. M. Emrich, X. Zhang, P. Xin, V. Arige, T. Pathak, J. C. Benson, M. T. Johnson, N. Lakomski, N. Hempel, J. M. Han, G. Dupont, D. I. Yule, J. Sneyd, M. Trebak

This study investigates how mitochondrial Ca2+ uniporter (MCU) regulates interorganellar Ca2+ signaling and NFAT activation, showing that MCU-KO increases cytosolic Ca2+ despite reduced CRAC channel activity.

bioRxiv · Apr 7, 2021Cell Biology