Author

L. D. Notarangelo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Approach:deep learning· 2 Assay:CITE-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Assay:imaging· 1

Frequent Co-Authors

F. Pala· 2 shared M. Bosticardo· 2 shared O. M. Delmonte· 2 shared A. Bodansky· 1 shared A. F. Kung· 1 shared A. J. Radtke· 1 shared A. Mitchell· 1 shared A. Sheikali· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

F. Pala

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Author profile →

3 papers

Recent·Most cited

A spatial human thymus cell atlas mapped to a continuous tissue axis

N. Yayon, V. R. Kedlian, L. Boehme, C. Suo, B. Wachter, R. T. Beuschel, O. Amsalem, K. Polanski, S. Koplev, E. Tuck, E. Dann, J. Van Hulle, S. Perera, T. Putteman, A. V. Predeus, , Tag

The paper maps the spatial organization of the human thymus across developmental stages using a multimodal atlas and identifies key cellular and molecular features of T cell development.

bioRxiv · Oct 25, 2023Immunology

Genetically Corrected RAG2-SCID Human Hematopoietic Stem CellsRestore V(D)J-Recombinase and Rescue Lymphoid Deficiency

M. Pavel-Dinu, C. L. Gardner, Y. Nakauchi, T. Kawai, O. M. Delmonte, B. Palterer, M. Bosticardo, F. Pala, S. Viel, H. L. Malech, H. Y. Ghanim, N. N. Bode, G. L. Kurgan, C. A. Vakulskas, A. Sheikali, , M. H. Porteus

This study corrects the RAG2 gene in human hematopoietic stem cells to restore V(D)J recombination and lymphoid development in RAG2-SCID patients.

bioRxiv · Jul 12, 2022Immunology

Autoantibody discovery across monogenic, acquired, and COVID19-associated autoimmunity with scalable PhIP-Seq

S. E. Vazquez, S. A. Mann, A. Bodansky, A. F. Kung, Z. Quandt, E. M. N. Ferre, N. Landegren, D. Eriksson, P. Bastard, S.-Y. Zhang, J. Liu, A. Mitchell, C. Mandel-Brehm, B. Miao, G. Sowa, , J. L. DeRisi

This paper scales PhIP-Seq for autoantibody discovery across multiple autoimmune diseases and COVID19, enabling machine learning predictions and identification of disease-specific autoantigens.

bioRxiv · Mar 23, 2022Immunology