Author

L. Doughty

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. P. Leis· 1 shared C. C. Kosasih· 1 shared C. J. Morton· 1 shared C. O. Zlatic· 1 shared E. Hanssen· 1 shared K. Aizel· 1 shared K. Y. Fung· 1 shared M. D. W. Griffin· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

A. P. Leis

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1 paper

Recent·Most cited

Structures of the interleukin 11 signalling complex reveal dynamics of gp130 extracellular domains and the inhibitory mechanism of a cytokine variant

R. D. Metcalfe, E. Hanssen, K. Y. Fung, K. Aizel, C. C. Kosasih, C. O. Zlatic, L. Doughty, C. J. Morton, A. P. Leis, M. W. Parker, P. R. Gooley, T. L. Putoczki, M. D. W. Griffin

This study presents cryo-EM and crystal structures of the IL-11 signalling complex, revealing dynamics of gp130 and the inhibitory mechanism of a cytokine variant.

bioRxiv · Jul 21, 2022Cell Biology