Author

C. J. Morton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

M. W. Parker· 2 shared A. P. Leis· 1 shared B. Bennetts· 1 shared C. C. Kosasih· 1 shared C. O. Zlatic· 1 shared E. Hanssen· 1 shared K. Aizel· 1 shared K. Y. Fung· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

M. W. Parker

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2 papers

Recent·Most cited

Structures of the interleukin 11 signalling complex reveal dynamics of gp130 extracellular domains and the inhibitory mechanism of a cytokine variant

R. D. Metcalfe, E. Hanssen, K. Y. Fung, K. Aizel, C. C. Kosasih, C. O. Zlatic, L. Doughty, C. J. Morton, A. P. Leis, M. W. Parker, P. R. Gooley, T. L. Putoczki, M. D. W. Griffin

This study presents cryo-EM and crystal structures of the IL-11 signalling complex, revealing dynamics of gp130 and the inhibitory mechanism of a cytokine variant.

bioRxiv · Jul 21, 2022Cell Biology

Mutations in an intracellular vestibule that bifurcates from the pore of ClC-1 chloride ion channels affect anion permeation

B. Bennetts, C. J. Morton, M. W. Parker

This study shows that structural differences outside the conserved Cl ion pathway in ClC-1 channels affect anion permeation by altering interactions between permeating anions and selectivity.

bioRxiv · Nov 1, 2020 · PreprintBiochemistry