Author

L. E. Smythies

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

D. K. Crossman· 2 shared K. L. Alexander· 2 shared P. D. Smith· 2 shared A. Chakraborty· 1 shared B. Shin· 1 shared C. A. Klug· 1 shared C. Britain· 1 shared C. S. Hunter· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

D. K. Crossman

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Author profile →

2 papers

Recent·Most cited

Novel Biomarkers and Distinct Transcriptomic Profile of Barrett's Esophagus Epithelial Stem Cells

K. L. Alexander, L. E. Smythies, K. R. Kyanam-Kabir-Baig, E. Poovey, D. K. Crossman, P. D. Smith, S. Peter

The paper identifies novel biomarkers and transcriptomic profiles in Barrett's esophagus epithelial stem cells, highlighting CT83 and ST6GAL1 as potential indicators for cancer progression.

bioRxiv · Aug 7, 2023 · PreprintCancer Biology

ST6GAL1 sialyltransferase promotes acinar to ductal metaplasia and pancreatic cancer progression

A. Chakraborty, N. Bhalerao, M. P. Marciel, J. Hwang, C. Britain, E. E. Eltoum, R. B. Jones, K. L. Alexander, L. E. Smythies, P. D. Smith, D. K. Crossman, M. R. Crowley, B. Shin, L. E. Harrington, Z. Yan, , S. L. Bellis

This study identifies ST6GAL1 sialyltransferase as a promoter of acinar-to-ductal metaplasia and pancreatic cancer progression through glycosylation-dependent mechanisms.

bioRxiv · Apr 28, 2022 · PreprintCancer Biology