Author

L. Engel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:cryo-EM· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Research Focus:imputation· 1

Frequent Co-Authors

A. R. Dunn· 3 shared W. I. Weis· 2 shared A. S. Vander Roest· 1 shared B. L. Pruitt· 1 shared B. M. Sow· 1 shared C. G. Vasquez· 1 shared D. Bernstein· 1 shared D. Hanein· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiophysics

A. R. Dunn

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Structure of the Thin Filament in Human iPSC-derived Cardiomyocytes and its Response to Heart Disease

R. A. Woldeyes, M. Nishiga, A. S. Vander Roest, L. Engel, P. Giri, G. C. Montenegro, A. R. Dunn, J. A. Spudich, D. Bernstein, M. F. Schmid, J. C. Wu, W. Chiu

This study uses cryo-ET to analyze the structure of thin filaments in human iPSC-derived cardiomyocytes and how they change with disease-related perturbations.

bioRxiv · Oct 26, 2023 · PreprintBiophysics

Extracellular filaments revealed by affinity capture cryo-electron tomography of lymphocytes

L. Engel, M. Zaoralova, M. Zhou, A. R. Dunn, S. L. Oliver

This study demonstrates an affinity capture method for preparing T-cells and Jurkat cells for cryo-ET, revealing extracellular filamentous structures and improving workflow efficiency.

bioRxiv · Aug 5, 2023 · PreprintCell Biology

Lattice micropatterning for cryo-electron tomography studies of cell-cell contacts

L. Engel, C. G. Vasquez, E. A. Montabana, B. M. Sow, M. P. Wakiewicz, W. I. Weis, A. R. Dunn

This study uses lattice micropatterning to improve the positioning of endothelial cells on EM grids, enabling more efficient cryo-electron tomography of cell-cell contacts.

bioRxiv · Aug 30, 2020Bioengineering

Extracellular matrix micropatterning technology for whole cell cryogenic electron microscopy studies

L. Engel, G. Gaietta, L. P. Dow, M. F. Swift, G. Pardon, N. Volkmann, W. I. Weis, D. Hanein, B. L. Pruitt

This paper introduces a technology to study mesoscale organization in epithelial cells under morphological modulation using ECM micropatterning for cryogenic electron microscopy.

bioRxiv · Jun 2, 2019Bioengineering