Author

L. F. Horowitz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 4 Approach:experimental assay· 4 Organism:human· 4 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:organoid / primary culture· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Folch· 4 shared A. D. Rodriguez· 2 shared K. Castro· 2 shared R. C. Rostomily· 2 shared R. J. Monnat· 2 shared R. S. Yeung· 2 shared A. Locke· 1 shared A. Mikheev· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersBioengineering

A. Folch

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Author profile →

4 papers

Recent·Most cited

Functional evaluation of microdissected tumor 'cuboids': a microscale ex vivo cancer model that retains a complex tumor microenvironment

L. F. Horowitz, R. A. Rodriguez-Mias, M. Chang, S. Zhu, Y. Tang, A. Locke, N. R. Gottshall, I. Stepanov, C. Stiles, M. Yeung, T. N. Nguyen, E. J. Lockhart, C. Ahls, E. Wayne, W. Wei, , A. Folch

The paper develops a microscale ex vivo cancer model using tumor cuboids that retain a complex tumor microenvironment, enabling drug and immunotherapy testing.

bioRxiv · Mar 22, 2024 · PreprintCancer Biology

A 96-WELL VALVED MICROFLUIDIC DEVICE FOR TESTING OF LIVE INTACT TUMOR CUBOIDS

E. Lockhart, L. F. Horowitz, C. Lim, T. Nguyen, M. Mehrabi, T. Gujral, A. Folch

The paper introduces a 96-well microfluidic device for testing drug responses in live tumor cuboids, preserving the tumor microenvironment for personalized oncology applications.

bioRxiv · Jul 7, 2022 · PreprintBioengineering

A Microfluidic Platform for Functional Testing of Cancer Drugs on Intact Tumor Slices

A. D. Rodriguez, L. F. Horowitz, K. Castro, H. Kenerson, N. Bhattacharjee, G. Gandhe, A. Raman, R. J. Monnat, R. S. Yeung, R. C. Rostomily, A. Folch

This paper develops a microfluidic platform for testing cancer drugs on intact tumor slices to improve drug response assessment in precision oncology.

bioRxiv · Mar 2, 2020Bioengineering

Multiplexed drug testing of tumor slices using a microfluidic platform

L. F. Horowitz, A. D. Rodriguez, Z. Dereli-Korkut, R. Lin, K. Castro, A. Mikheev, R. J. Monnat, A. Folch, R. C. Rostomily

This paper develops a microfluidic platform for rapid, multiplexed drug testing of cancer slices to guide personalized therapy.

bioRxiv · Feb 25, 2020Bioengineering