Author

R. J. Monnat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

A. D. Rodriguez· 2 shared A. Folch· 2 shared K. Castro· 2 shared L. F. Horowitz· 2 shared R. C. Rostomily· 2 shared W. Tang· 2 shared A. D. Mitchell· 1 shared A. G. Paulovich· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBioengineering

A. D. Rodriguez

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Mutation Patterns Predict Drug Sensitivity in Acute Myeloid Leukemia

G. Qin, J. Dai, S. Chien, T. J. Martins, B. Loera, Q. Nguyen, M. L. Oakes, B. Tercan, B. Aguilar, L. Hagen, J. McCune, R. Gelinas, R. J. Monnat, I. Shmulevich, P. S. Becker

The paper identifies mutation patterns linked to drug sensitivity in AML using integrated computational and experimental analysis.

bioRxiv · May 24, 2023Cell Biology

Fanconi anemia-isogenic head and neck cancer cell line pairs - a basic and translational science resource

H. T. Nguyen, W. Tang, A. L. H. Webster, J. R. Whiteaker, C. M. Chandler, R. Errazquin, L. B. Sullivan, E. Jonlin, E. E. Hoskins, E. Y. Chen, M. Fritzke, A. G. Paulovich, S. I. Wells, K. Roohollahi, J. Dorsman, , R. J. Monnat

The paper develops isogenic head and neck cancer cell line pairs to study Fanconi anemia-associated cancers and their treatment.

bioRxiv · Sep 11, 2022Cancer Biology

A Microfluidic Platform for Functional Testing of Cancer Drugs on Intact Tumor Slices

A. D. Rodriguez, L. F. Horowitz, K. Castro, H. Kenerson, N. Bhattacharjee, G. Gandhe, A. Raman, R. J. Monnat, R. S. Yeung, R. C. Rostomily, A. Folch

This paper develops a microfluidic platform for testing cancer drugs on intact tumor slices to improve drug response assessment in precision oncology.

bioRxiv · Mar 2, 2020Bioengineering

Multiplexed drug testing of tumor slices using a microfluidic platform

L. F. Horowitz, A. D. Rodriguez, Z. Dereli-Korkut, R. Lin, K. Castro, A. Mikheev, R. J. Monnat, A. Folch, R. C. Rostomily

This paper develops a microfluidic platform for rapid, multiplexed drug testing of cancer slices to guide personalized therapy.

bioRxiv · Feb 25, 2020Bioengineering

An RNAi screen in human cell lines reveals conserved DNA damage repair pathways that mitigate formaldehyde sensitivity

E. Juarez, N. Chambwe, W. Tang, A. D. Mitchell, N. Owen, A. Kumari, R. J. Monnat, A. McCullough

The paper identifies DNA damage repair pathways that reduce formaldehyde toxicity in human cell lines and shows their conservation in budding yeast.

bioRxiv · Apr 30, 2018Cell Biology