Author

L. Folkes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. E. Munsterberg· 1 shared A. J. Ryan· 1 shared A. Nandakumar· 1 shared C. Utting· 1 shared D. Blackwell· 1 shared D. Ebner· 1 shared E. Poschl· 1 shared E. Seraia· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

A. E. Munsterberg

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Author profile →

2 papers

Recent·Most cited

Muscle stem cell function is impaired in absence of Talpid3 - a gene required for primary cilia formation

V. Martinez-Heredia, D. Blackwell, S. Sebastian, T. Pearson, G. F. Mok, L. Mincarelli, C. Utting, L. Folkes, E. Poschl, I. C. Macaulay, U. C. Mayer, A. E. Munsterberg

This study shows that Talpid3 is essential for muscle stem cell self-renewal and regeneration, and pharmacological Wnt activation can restore regeneration in its absence.

bioRxiv · Oct 14, 2022Cell Biology

IGF targeting perturbs global replication through ribonucleotide reductase dysfunction

G. Rieunier, X. Wu, L. Harris, J. Mills, A. Nandakumar, L. Colling, E. Seraia, S. B. Hatch, D. Ebner, L. Folkes, U. Weyer-czernilofsky, T. Bogenrieder, A. J. Ryan, V. M. Macaulay

This study shows that IGF-1R inhibition causes replication stress by reducing RNR subunit RRM2, leading to DNA damage and synthetic lethality with ATM loss in cancer cells.

bioRxiv · Aug 11, 2020Cancer Biology