Author

L. Gutgesell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Ashkenazi· 1 shared A. Le Thomas· 1 shared A. Murthy· 1 shared D. A. Lawrence· 1 shared G. Strasser· 1 shared I. Mellman· 1 shared J. M. Harnoss· 1 shared O. Guttman· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

A. Ashkenazi

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1 paper

Recent·Most cited

Antigen-derived peptides directly engage the unfolded-protein sensor IRE1α to curb cross-presentation by dendritic cells

O. Guttman, A. Le Thomas, S. A. Marsters, D. A. Lawrence, L. Gutgesell, J. M. Harnoss, S. M. Haag, A. Murthy, G. Strasser, Z. Modrusan, T. Wu, I. Mellman, A. Ashkenazi

The paper shows antigen-derived peptides activate IRE1α in dendritic cells, reducing MHC-I expression and cross-presentation, and demonstrates that IRE1 inhibition enhances anti-tumor immunity.

bioRxiv · Sep 10, 2021Cell Biology