Genome edited colorectal cancer organoid models reveal distinct microRNA activity patterns across different mutation profiles
J. W. Villanueva, L. Kwong, T. Han, S. A. Martinez, F. C. Pan, M. T. Shanahan, M. Kanke, S. Chen, L. E. Dow, C. G. Danko, P. Sethupathy
The paper uses genome-edited colorectal cancer organoids to identify microRNA expression patterns linked to specific mutation profiles and shows miR-24-3p's role in promoting cancer cell survival.
bioRxiv · Dec 13, 2021 · PreprintCancer Biology