A. Hubbard

Structural basis for catalysis and selectivity of phospholipid synthesis by eukaryotic choline-phosphotransferase

The paper presents the structure of yeast CPT1 in multiple substrate-bound states to elucidate the mechanism of phospholipid synthesis and selectivity.

A lineage-specific Exo70 is required for receptor kinase-mediated immunity in barley

The paper identifies a lineage-specific Exo70FX12 gene required for Rps8-mediated immunity in barley against wheat stripe rust.

PolyA-modulating antisense oligonucleotides reveal opposing functions for long non-coding RNA NEAT1 isoforms in neuroblastoma

The paper develops antisense oligonucleotides to modulate NEAT1 isoform ratios in neuroblastoma, showing increased NEAT1_2 and reduced cell viability.

Effect of sanitation improvements on soil-transmitted helminth eggs in courtyard soil from rural Bangladesh: Evidence from a cluster-randomized controlled trial

This study evaluates a sanitation program's effect on reducing soil-transmitted helminth eggs in courtyard soil, finding no significant impact despite high latrine uptake.

Piperacillin/tazobactam resistant, cephalosporin susceptible Escherichia coli bloodstream infections are driven by multiple acquisition of resistance across diverse sequence types

The paper identifies genetic diversity and resistance mechanisms in E. coli with piperacillin/tazobactam resistance but third-generation cephalosporin susceptibility.

Isolation of an antimicrobial resistant, biofilm forming, Klebsiella grimontii isolate from a re-usable water bottle.

The paper isolates a Klebsiella grimontii strain from a re-usable water bottle, identifies its antimicrobial resistance and biofilm-forming capabilities, and highlights hygiene concerns for reusable bottles.

Illuminating the functional rare biosphere of the Greenland Ice Sheet’s Dark Zone

The paper analyzes microbial communities in the Greenland Ice Sheet’s Dark Zone using 16S rRNA gene and cDNA data to reveal the role of rare taxa in albedo reduction and melting.