Author

S. A. Martinez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

B. Lim· 1 shared C. G. Danko· 1 shared E. B. Goff· 1 shared F. C. Pan· 1 shared G. V. Echeverria· 1 shared J. Lee· 1 shared J. P. Barrish· 1 shared J. W. Villanueva· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

B. Lim

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Author profile →

2 papers

Recent·Most cited

Mitochondrial structure and function adaptation in residual triple negative breast cancer cells surviving chemotherapy treatment

M. L. Baek, J. Lee, K. E. Pendleton, M. J. Berner, E. B. Goff, L. Tan, S. A. Martinez, T. Wang, M. D. Meyer, B. Lim, J. P. Barrish, W. Porter, P. L. Lorenzi, G. V. Echeverria

This study identifies how residual triple negative breast cancer cells adapt mitochondrial structure and function to survive chemotherapy, showing that DNA-damaging agents promote mitochondrial fusion and OXPHOS, which can be targeted with OPA1 inhibitors.

bioRxiv · Feb 25, 2022Cancer Biology

Genome edited colorectal cancer organoid models reveal distinct microRNA activity patterns across different mutation profiles

J. W. Villanueva, L. Kwong, T. Han, S. A. Martinez, F. C. Pan, M. T. Shanahan, M. Kanke, S. Chen, L. E. Dow, C. G. Danko, P. Sethupathy

The paper uses genome-edited colorectal cancer organoids to identify microRNA expression patterns linked to specific mutation profiles and shows miR-24-3p's role in promoting cancer cell survival.

bioRxiv · Dec 13, 2021 · PreprintCancer Biology