Author

L. M. Alkhalaf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

G. L. Challis· 2 shared C. Corre· 1 shared C. Hobson· 1 shared D. Rea· 1 shared F. Pang· 1 shared H. Bhukya· 1 shared H. Venugopal· 1 shared K. M. Styles· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

G. L. Challis

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2 papers

Recent·Most cited

Antibiotic skeletal diversification via differential enoylreductase recruitment and module iteration in trans-acyltransferase polyketide synthases

X. Jian, F. Pang, C. Hobson, M. Jenner, L. M. Alkhalaf, G. L. Challis

The paper investigates how structural diversity in polyketide antibiotics arises through differential enoylreductase recruitment and module iteration in trans-acyltransferase polyketide synthases.

bioRxiv · Nov 30, 2023 · PreprintBiochemistry

Structural basis for control of antibiotic production by bacterial hormones

S. Zhou, H. Bhukya, N. Malet, P. J. Harrison, D. Rea, M. J. Belousoff, H. Venugopal, P. K. Sydor, K. M. Styles, L. Song, M. J. Cryle, L. M. Alkhalaf, V. Fülöp, G. L. Challis, C. Corre

This study determines the structural basis for hormone-controlled antibiotic production in Actinobacteria by solving the X-ray structure of an MmfR-AHFCA complex and elucidating DNA release mechanisms.

bioRxiv · May 2, 2020Biochemistry