Author

A. Kant

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Research Focus:chromatin & epigenetic regulation· 3 Approach:deep learning· 2 Assay:ChIP-seq· 1 Assay:Hi-C· 1 Assay:imaging· 1

Frequent Co-Authors

M. Lakadamyali· 2 shared V. B. Shenoy· 2 shared Z. Guo· 2 shared A. E. Loneker· 1 shared E. Pujadas· 1 shared F. Alisafaei· 1 shared L. M. Almassalha· 1 shared M. Dhankhar· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBiophysics

M. Lakadamyali

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Revealing the Biophysics of Lamina-Associated Domain Formation by Integrating Theoretical Modeling and High-Resolution Imaging

M. Dhankhar, Z. Guo, A. Kant, R. Basir, R. Joshi, S. C. Heo, R. L. Mauck, M. Lakadamyali, V. B. Shenoy

This study combines theoretical modeling and high-resolution imaging to reveal how chromatin-lamina interactions and environmental cues influence LAD formation and thickness in hMSCs.

bioRxiv · Jun 24, 2024Biophysics

Chemo-Mechanical Regulation of Tau Phosphorylation Following Traumatic Brain Injuries

A. Kant, N. V. Medhekar, T. K. Bhandakkar

This study develops a computational model to predict tau hyperphosphorylation after traumatic brain injuries by linking mechanical stress and calcium signaling.

bioRxiv · Jul 13, 2023 · PreprintBiophysics

Active Transcription and Epigenetic Reactions Synergistically RegulateMeso-Scale Genomic Organization

A. Kant, Z. Guo, V. Vinayak, M. V. Neguembor, W. S. Li, V. Agrawal, E. Pujadas, L. M. Almassalha, V. Backman, M. Lakadamyali, M. P. Cosma, V. Shenoy

This study introduces a mesoscale model to show how transcription and epigenetic reactions regulate heterochromatin domain sizes, finding that transcription loss increases domain size and compaction.

bioRxiv · Apr 21, 2023Biophysics

Lipid droplets are intracellular mechanical stressors that promote hepatocyte dedifferentiation

A. E. Loneker, F. Alisafaei, A. Kant, P. A. Janmey, V. B. Shenoy, R. G. Wells

This study shows lipid droplets act as intracellular mechanical stressors that cause nuclear deformation and hepatocyte dedifferentiation, similar to tissue stiffening effects.

bioRxiv · Aug 27, 2022 · PreprintCell Biology