Author

L. M. Figueiredo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 5 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Beaver· 1 shared A. Lamy· 1 shared A. M. Nascimento· 1 shared B. Bobb· 1 shared B. L. Weiss· 1 shared B. Zhang· 1 shared C. A. Franco· 1 shared C. Notredame· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperMicrobiology

A. Beaver

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Adipocyte lipolysis protects the host against Trypanosoma brucei infection

H. Machado, P. Hofer, R. Zechner, L. M. Figueiredo

This study shows that adipocyte lipolysis during Trypanosoma brucei infection reduces parasite burden and fat mass, acting as a host-protective mechanism.

bioRxiv · Nov 5, 2022 · PreprintMicrobiology

Extravascular spaces are the primary reservoir of antigenic diversity in Trypanosoma brucei infection

A. Beaver, Z. Keneskhanova, R. O. Cosentino, B. L. Weiss, E. O. Awuoche, G. M. Smallenberger, G. Y. Buenconsejo, N. P. Crilly, J. E. Smith, J. M. Hakim, B. Zhang, B. Bobb, F. Rijo-Ferreira, L. M. Figueiredo, S. Aksoy, , M. R. Mugnier

The paper shows that extravascular spaces, not the bloodstream, are the main source of antigenic diversity in Trypanosoma brucei infections, with over 75% of VSGs found exclusively in these spaces.

bioRxiv · Jun 27, 2022Microbiology

A novel lipase with dual localisation in Trypanosoma brucei

S. Monic, A. Lamy, T. Magali, T. Bizarra-Rebelo, F. Bringaud, T. K. Smith, L. M. Figueiredo, L. Riviere

The paper identifies a novel lipase in Trypanosoma brucei with dual localization and excretion, suggesting its potential as a diagnostic tool.

bioRxiv · Feb 23, 2022Microbiology

Organotypic endothelial adhesion molecules are key for Trypanosoma brucei tropism and virulence

M. De Niz, D. Bras, M. Pedro, A. M. Nascimento, C. A. Franco, L. M. Figueiredo

This study identifies organ-specific adhesion molecules critical for Trypanosoma brucei tissue tropism and virulence by showing their role in extravasation and reservoir establishment.

bioRxiv · Feb 26, 2021Microbiology

A long non-coding RNA controls parasite differentiation in African trypanosomes

F. Guegan, F. Bento, D. Neves, M. Sequeira, C. Notredame, L. M. Figueiredo

This study identifies a long non-coding RNA, Grumpy, that promotes premature differentiation of Trypanosoma brucei into the stumpy form, reducing parasite load and increasing host survival.

bioRxiv · May 3, 2020 · PreprintMicrobiology