Author

L. M. Leon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Assay:CRISPR screen· 1 Assay:DNA methylation· 1

Frequent Co-Authors

J. Bondy-Denomy· 2 shared A. E. Park· 1 shared A. L. Borges· 1 shared D. Agard· 1 shared E. S. Nieweglowska· 1 shared J. D. Berry· 1 shared J. Zhang· 1 shared S. D. Mendoza· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersMicrobiology

J. Bondy-Denomy

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Author profile →

2 papers

Recent·Most cited

Mobile element warfare via CRISPR and anti-CRISPR in Pseudomonas aeruginosa

L. M. Leon, A. E. Park, A. L. Borges, J. Zhang, J. Bondy-Denomy

This study identifies seven new anti-CRISPR proteins and characterizes their mechanisms against Type I-C CRISPR-Cas systems in Pseudomonas aeruginosa, revealing co-evolutionary dynamics between MGEs.

Nucleic Acids Research · Feb 5, 2021Peer-reviewedMicrobiology

A nucleus-like compartment shields bacteriophage DNA from CRISPR-Cas and restriction nucleases

S. D. Mendoza, J. D. Berry, E. S. Nieweglowska, L. M. Leon, D. Agard, J. Bondy-Denomy

This study identifies a nucleus-like compartment in a jumbo phage that protects its DNA from CRISPR-Cas and restriction nucleases, but leaves its mRNA vulnerable to Cas13a.

bioRxiv · Jul 17, 2018Microbiology