Author

S. D. Mendoza

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:CRISPR screen· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

J. Bondy-Denomy· 2 shared A. Oromi-Bosch· 1 shared D. Agard· 1 shared E. S. Nieweglowska· 1 shared J. Berry· 1 shared J. D. Berry· 1 shared J. Guan· 1 shared L. M. Leon· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

J. Bondy-Denomy

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2 papers

Recent·Most cited

RNA targeting with CRISPR-Cas13a facilitates bacteriophage genome engineering

J. Guan, A. Oromi-Bosch, S. D. Mendoza, S. Karambelkar, J. Berry, J. Bondy-Denomy

This paper develops a CRISPR-Cas13a-based method to edit bacteriophage genomes, enabling precise gene modifications and functional studies of phage genes.

bioRxiv · Feb 14, 2022 · PreprintMicrobiology

A nucleus-like compartment shields bacteriophage DNA from CRISPR-Cas and restriction nucleases

S. D. Mendoza, J. D. Berry, E. S. Nieweglowska, L. M. Leon, D. Agard, J. Bondy-Denomy

This study identifies a nucleus-like compartment in a jumbo phage that protects its DNA from CRISPR-Cas and restriction nucleases, but leaves its mRNA vulnerable to Cas13a.

bioRxiv · Jul 17, 2018Microbiology