Author

L. M. Perez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

C. A. Mesaros· 1 shared C. Loitz· 1 shared C. McCabe· 1 shared D. Nayak· 1 shared D. Vander Griend· 1 shared G. Prins· 1 shared H. Tang· 1 shared J. Garcia· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

C. A. Mesaros

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Author profile →

2 papers

Recent·Most cited

Epigenetic disruption of the RARγ complex impairs its function to bookmark AR enhancer interactions required for enzalutamide sensitivity in prostate cancer

S. A. Wani, S. Hussain, J. S. Gray, D. Nayak, H. Tang, L. M. Perez, M. D. Long, M. Siddappa, C. McCabe, L. Campbell, M. R. Freeman, M. J. Campbell

This study identifies RARγ's role in bookmarking AR enhancer interactions in prostate cancer, showing its impact on enzalutamide sensitivity and lineage plasticity.

bioRxiv · Dec 15, 2023 · PreprintCancer Biology

Regulation of prostate androgens by megalin and 25-hydroxyvitamin D status: Mechanism for high prostate androgen in African American men

J. Garcia, K. Krieger, C. Loitz, L. M. Perez, Z. A. Richards, Y. B. Helou, S. Kregel, S. Selada, C. A. Mesaros, P. Gann, T. E. Willnow, D. Vander Griend, R. Kittles, G. Prins, T. Penning, L. Nonn

This study shows megalin regulates prostate androgen levels by importing testosterone bound to sex hormone-binding globulin, and 25-hydroxyvitamin D suppresses megalin, linking vitamin D deficiency to higher prostate androgens in African American men.

bioRxiv · Nov 9, 2021Cancer Biology