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Prostate-derived circulating microRNAs add prognostic value to prostate cancer risk calculators

The paper identifies prostate-derived microRNAs in serum and extracellular vesicles that improve prostate cancer risk prediction models.

Vitamin D receptor cistrome-transcriptome analyses establishes quantitatively distinct receptor genomic interactions in African American prostate cancer regulated by BAZ1A

The paper analyzes VDR genomic interactions in African American prostate cancer cells and identifies BAZ1A as a regulator of VDR-dependent transcriptional responses.

Regulation of prostate androgens by megalin and 25-hydroxyvitamin D status: Mechanism for high prostate androgen in African American men

This study shows megalin regulates prostate androgen levels by importing testosterone bound to sex hormone-binding globulin, and 25-hydroxyvitamin D suppresses megalin, linking vitamin D deficiency to higher prostate androgens in African American men.

Vitamin D Sufficiency Enhances Differentiation of Patient-Derived Prostate Epithelial Organoids

This study shows that vitamin D sufficiency promotes differentiation of prostate epithelial organoids by inhibiting Wnt signaling, linking vitamin D deficiency to aggressive prostate cancer.

Cell-type specific expression of oncogenic and tumor suppressive microRNAs in the human prostate and prostate cancer

The paper quantifies miRNA expression in prostate stroma and epithelium, finding cell-type specific patterns and associations with prostate cancer recurrence.