Author

L. M. Pieper

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

P. J. Turnbaugh· 2 shared P. Spanogiannopoulos· 2 shared A. Wright· 1 shared B. K. Shoichet· 1 shared B. Vora· 1 shared C. Miller· 1 shared E. Tsakalozou· 1 shared H.-C. Chien· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

P. J. Turnbaugh

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Author profile →

2 papers

Recent·Most cited

The global anaerobic metabolism regulator fnr is necessary for the degradation of food dyes and drugs by Escherichia coli

L. M. Pieper, P. Spanogiannopoulos, R. Volk, C. Miller, A. Wright, P. J. Turnbaugh

This paper shows that the FNR regulator in E. coli is essential for azo bond degradation in the gut, influenced by oxygen and cysteine levels.

bioRxiv · Oct 25, 2022 · PreprintMicrobiology

Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives

L. Zou, P. Spanogiannopoulos, H.-C. Chien, L. M. Pieper, W. Cai, N. Khuri, J. Pottel, B. Vora, Z. Ni, E. Tsakalozou, W. Zhang, B. K. Shoichet, K. M. Giacomini, P. J. Turnbaugh

The paper identifies food and drug additives that inhibit intestinal drug transporters and shows gut bacteria can inactivate these additives, reducing their inhibitory effect.

bioRxiv · Oct 28, 2019Pharmacology & Toxicology