Modular capsid decoration boosts adenovirus vaccine-induced humoral and cellular immunity against SARS-CoV-2
M. D. J. Dicks, L. M. Rose, L. A. H. Bowman, C. Graham, K. J. Doores, M. H. Malim, S. J. Draper, M. Howarth, S. Biswas
This paper describes a method to enhance adenovirus vaccine efficacy by decorating capsid surfaces with antigens, resulting in improved humoral immunity and retained T cell responses.
bioRxiv · Feb 20, 2022Bioengineering