Author

L. McDonald

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. D. Diehl· 1 shared A. Deslattes Mays· 1 shared A. Schuettelkopf· 1 shared A. V. Pankajam· 1 shared B. Peng· 1 shared B. Xu· 1 shared C. Kelly· 1 shared C. Mackay· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioinformatics

A. D. Diehl

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Author profile →

3 papers

Recent·Most cited

A trustworthy semantic knowledge network linking data-driven cell phenotypes to diseases and drugs

B. Xu, A. Deslattes Mays, M. Diller, R. LeClair, A. V. Pankajam, W. Spear, D. Osumi-Sutherland, K. Arvind, S. Chatterjee, A. D. Diehl, M. M. Islam, C. Kelly, R. Khalil, J. Khare, R. Lopez Candelaria, , Richard H. Scheuermann

The paper develops NLM-CKN, a semantic knowledge network linking cell phenotypes to diseases and drugs using integrated data from 88 datasets.

bioRxiv · Nov 4, 2026 · PreprintBioinformatics

Salt-inducible kinase (SIK) inhibition is protective in a mouse model of asthma

M. van Gijsel-Bonnello, N. J. Darling, L. McDonald, M. Sime, J. Clark, M. Mezna, A. Schuettelkopf, C. Mackay, J. Bower, H. McKinnon, P. Cohen, S. Arthur

This study shows that inhibiting SIKs reduces IL-13 secretion from ILC2s and alleviates allergic asthma symptoms in mice.

bioRxiv · Jun 7, 2021 · PreprintImmunology

An atypical DYRK kinase connects quorum-sensing with posttranscriptional gene regulation in Trypanosoma brucei

M. Cayla, L. McDonald, P. MacGregor, K. Matthews

This study identifies TbDYRK, an atypical DYRK kinase in Trypanosoma brucei, linking quorum sensing with posttranscriptional gene regulation through phosphorylation of TbZC3H20.

bioRxiv · Sep 18, 2019Microbiology