Author

L. N. Enserink

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

C. Veldman· 1 shared I. J. Nijman· 1 shared M. A. Ratze· 1 shared M. Christgen· 1 shared N. Ishiyama· 1 shared P. J. van Diest· 1 shared P. W. Derksen· 1 shared R. R. Bernards· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

C. Veldman

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintJul 4, 2023

Somatic mutation of Afadin leads to anchorage independent survival and metastatic growth of breast cancer through alpha E-catenin dependent destabilization of the adherens junction

M. A. Ratze, L. N. Enserink, N. Ishiyama…·P. W. Derksen

This study identifies a somatic Afadin mutation that destabilizes adherens junctions and promotes metastatic growth in breast cancer by disrupting E-catenin binding.

DOI 10.1101/2023.07.04.547654

humanwhole-genome sequencing

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