Author

L. R. Duhamel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

J. A. Stinson· 2 shared J. R. Palmeri· 2 shared K. D. Wittrup· 2 shared L. Santollani· 2 shared W. Pinney· 2 shared B. D. Bryson· 1 shared B. M. Lax· 1 shared D. J. Irvine· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersImmunology

J. A. Stinson

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Author profile →

2 papers

Recent·Most cited

Local delivery of cell surface-targeted immunocytokines programs systemic anti-tumor immunity

L. Santollani, Y. J. Zhang, L. Maiorino, J. R. Palmeri, J. A. Stinson, L. R. Duhamel, K. Qureshi, J. R. Suggs, O. T. Porth, W. Pinney, R. Al Msari, K. D. Wittrup, D. J. Irvine

This study develops CD45-targeted immunocytokines that localize to immune cells in tumors and lymph nodes, eradicating both treated and distant tumors in mouse models.

bioRxiv · Jan 3, 2024 · PreprintImmunology

Tregs constrain CD8+ T cell priming required for curative intratumorally anchored anti-4-1BB immunotherapy

J. R. Palmeri, B. M. Lax, J. M. Peters, L. R. Duhamel, J. A. Stinson, L. Santollani, E. A. Lutz, W. Pinney, B. D. Bryson, K. D. Wittrup

The paper shows that inhibiting Tregs enhances CD8+ T cell priming, improving antitumor responses to 4-1BB combination therapy.

bioRxiv · Jan 30, 2023 · PreprintImmunology