Author

L. Maiorino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Assay:CITE-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

D. J. Irvine· 4 shared K. D. Wittrup· 2 shared S. Wu· 2 shared A. Aguirre· 1 shared A. Aung· 1 shared A. Jefferson· 1 shared A. K. Chakraborty· 1 shared A. K. Shalek· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersImmunology

D. J. Irvine

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Local delivery of cell surface-targeted immunocytokines programs systemic anti-tumor immunity

L. Santollani, Y. J. Zhang, L. Maiorino, J. R. Palmeri, J. A. Stinson, L. R. Duhamel, K. Qureshi, J. R. Suggs, O. T. Porth, W. Pinney, R. Al Msari, K. D. Wittrup, D. J. Irvine

This study develops CD45-targeted immunocytokines that localize to immune cells in tumors and lymph nodes, eradicating both treated and distant tumors in mouse models.

bioRxiv · Jan 3, 2024 · PreprintImmunology

Two-dose "extended priming" immunization amplifies humoral immune responses by synchronizing vaccine delivery with the germinal center response

S. Bhagchandani, L. Yang, L. Maiorino, E. Ben-Akiva, K. A. Rodrigues, A. Romanov, H. Suh, A. Aung, S. Wu, A. Wadhera, A. K. Chakraborty, D. J. Irvine

This study shows that a two-dose extended priming vaccine regimen enhances humoral immune responses by synchronizing antigen delivery with germinal center dynamics.

bioRxiv · Nov 20, 2023 · PreprintImmunology

Cancer tissue of origin constrains the growth and metabolism of metastases

S. Sivanand, Y. Gultekin, P. Winter, S. Y. Vermeulen, K. Tchourine, K. L. Abbott, L. V. Danai, F. Gourgue, B. T. Do, K. Crowder, T. Kunchok, A. N. Lau, A. M. Darnell, A. Jefferson, S. Morita, , M. G. Vander Heiden

This study shows that cancer tissue-of-origin influences the metabolism and growth preferences of both primary and metastatic tumors.

bioRxiv · Aug 17, 2022Cancer Biology

Identification of highly cross-reactive mimotopes for a public T cell response in murine melanoma

B. E. Grace, C. M. Backlund, D. M. Morgan, B. H. Kang, N. K. Singh, B. D. Huisman, C. G. Rappazzo, K. D. Moynihan, L. Maiorino, C. S. Dobson, T. Kyung, K. S. Gordon, P. V. Holec, O. C. T. Mbah, D. Garafola, , M. E. Birnbaum

The paper identifies a dominant tumor-associated antigen in murine melanoma and shows that engineered mimotopes can induce cross-reactive T cell responses.

bioRxiv · Feb 28, 2022Immunology