Author

L. Rizzello

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

E. Scarpa· 3 shared G. Battaglia· 2 shared V. M. Gouveia· 2 shared A. Duro-Castano· 1 shared A. Griego· 1 shared A. Oliveira· 1 shared A. Poma· 1 shared A. Spitaleri· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersMicrobiology

E. Scarpa

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Endolysin B: A new archetype in M. tuberculosis treatment

A. Griego, B. Antinori, A. Spitaleri, I. Muzzolini, S. Muzzioli, L. Calo, G. Moschetti, M. Genta, E. Scarpa, V. De Matteis, R. Miggiano, S. Ricagno, L. Rizzello

This study demonstrates that Ms6LysB can impair M. tuberculosis growth and retain lytic properties when internalized by macrophages, suggesting its potential as a new therapeutic strategy.

bioRxiv · Dec 5, 2023 · PreprintMicrobiology

A Multiscale study of phosphorylcholine driven cellular phenotypic targeting

S. Acosta-Gutierrez, D. Matias, M. Avila-Olias, V. M. Gouveia, E. Scarpa, J. Forth, C. Contini, A. Duro-Castano, L. Rizzello, G. Battaglia

This study demonstrates how promiscuous ligands can be used to create multiplexed-multivalent carriers for phenotypic targeting, showing that PMPC-PDPA polymersomes can target monocytes in vivo.

bioRxiv · Feb 9, 2022Biochemistry

Targeting activated macrophages intracellular milieu to augment anti-inflammatory drug potency

V. M. Gouveia, L. Rizzello, B. Vidal, C. Nunes, A. Poma, C. Lopez-Vasquez, E. Scarpa, S. Brander, A. Oliveira, J. E. Fonseca, S. Reis, G. Battaglia

This study demonstrates that pH-responsive polymersomes enhance methotrexate delivery to activated macrophages, improving arthritis treatment while reducing off-target effects.

bioRxiv · Jun 22, 2021Immunology