Author

E. Scarpa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1 Bioengineering· 1 Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 3 Assay:imaging· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2

Frequent Co-Authors

B. Sanson· 3 shared G. Battaglia· 3 shared L. Rizzello· 3 shared A. Duro-Castano· 2 shared L. Muresan· 2 shared V. M. Gouveia· 2 shared A. Griego· 1 shared A. Oliveira· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersBiophysics

B. Sanson

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Endolysin B: A new archetype in M. tuberculosis treatment

A. Griego, B. Antinori, A. Spitaleri, I. Muzzolini, S. Muzzioli, L. Calo, G. Moschetti, M. Genta, E. Scarpa, V. De Matteis, R. Miggiano, S. Ricagno, L. Rizzello

This study demonstrates that Ms6LysB can impair M. tuberculosis growth and retain lytic properties when internalized by macrophages, suggesting its potential as a new therapeutic strategy.

bioRxiv · Dec 5, 2023 · PreprintMicrobiology

Mechanical stress combines with planar polarised patterning during metaphase to orient embryonic epithelial cell divisions

G. Blanchard, E. Scarpa, L. Muresan, B. Sanson

The paper shows that mechanical stress and planar polarisation interact during metaphase to orient cell divisions in Drosophila embryos, influencing body axis elongation.

bioRxiv · Jul 12, 2023Biophysics

A Multiscale study of phosphorylcholine driven cellular phenotypic targeting

S. Acosta-Gutierrez, D. Matias, M. Avila-Olias, V. M. Gouveia, E. Scarpa, J. Forth, C. Contini, A. Duro-Castano, L. Rizzello, G. Battaglia

This study demonstrates how promiscuous ligands can be used to create multiplexed-multivalent carriers for phenotypic targeting, showing that PMPC-PDPA polymersomes can target monocytes in vivo.

bioRxiv · Feb 9, 2022Biochemistry

Targeting activated macrophages intracellular milieu to augment anti-inflammatory drug potency

V. M. Gouveia, L. Rizzello, B. Vidal, C. Nunes, A. Poma, C. Lopez-Vasquez, E. Scarpa, S. Brander, A. Oliveira, J. E. Fonseca, S. Reis, G. Battaglia

This study demonstrates that pH-responsive polymersomes enhance methotrexate delivery to activated macrophages, improving arthritis treatment while reducing off-target effects.

bioRxiv · Jun 22, 2021Immunology

Combinatorial Intracellular Delivery Screening (CIDS) of Anticancer Drugs

B. Sola-Barrado, D. Moreira-Leite, E. Scarpa, A. Duro-Castano, G. Battaglia

This study introduces a method using PMPC-PDPA polymersomes to enhance intracellular delivery of poorly water-soluble anticancer drugs and identifies synergistic drug combinations.

bioRxiv · Aug 28, 2020Bioengineering

Joint Motion Estimation and Source Identification using Convective Regularisation with an Application to the Analysis of Laser Nanoablations

L. F. Lang, N. Dutta, E. Scarpa, B. Sanson, C.-B. Schoenlieb, J. Etienne

The paper develops a variational method for joint motion estimation and source identification in 1D image sequences, applied to analyze laser nanoablations in Drosophila embryos.

bioRxiv · Jul 2, 2019 · PreprintBiophysics

Par3/Baz levels control epithelial folding at actomyosin-enriched compartmental boundaries

J. M. Urbano, H. W. Naylor, E. Scarpa, L. Muresan, B. Sanson

This study shows that Par3/Baz levels control epithelial folding at actomyosin-enriched compartmental boundaries in Drosophila embryos.

bioRxiv · Apr 10, 2017Cell Biology