Author

L. Schecterson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:cryo-EM· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

B. M. Gumbiner· 2 shared A. Maker· 1 shared B. Hammerson· 1 shared B. Staker· 1 shared B. Xie· 1 shared J. Abendroth· 1 shared M. Bolejack· 1 shared P. J. Myler· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

B. M. Gumbiner

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Strengthening E-cadherin adhesion via antibody mediated binding stabilization.

B. Xie, S. Xu, L. Schecterson, B. M. Gumbiner, S. Sivasankar

This study identifies how the monoclonal antibody 66E8 stabilizes E-cadherin adhesion by stabilizing the strand-swap dimer conformation through electrostatic interactions.

bioRxiv · Jul 4, 2023Biophysics

Regulation of multiple dimeric states of E-cadherin by adhesion activating antibodies revealed through Cryo-EM and X-ray crystallography

A. Maker, M. Bolejack, L. Schecterson, B. Hammerson, J. Abendroth, T. E. Edwards, B. Staker, P. J. Myler, B. M. Gumbiner

The paper uses Cryo-EM and X-ray crystallography to reveal how activating antibodies regulate E-cadherin dimer states through structural changes and interactions.

bioRxiv · Mar 21, 2022Biochemistry