Author

L. Somasundaram

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

C. Xu· 1 shared D. Baker· 1 shared D. Ehnes· 1 shared D. L. Sellers· 1 shared D. Wang· 1 shared E. Troemel· 1 shared G. Ueda· 1 shared G. Xu· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

C. Xu

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2 papers

Recent·Most cited

F-domain valency determines outcome of signaling through the angiopoietin pathway

Y. T. Zhao, J. A. Fallas, S. Saini, G. Ueda, L. Somasundaram, Z. Zhou, I. Xavier, D. Ehnes, C. Xu, L. Carter, S. Wrenn, J. Mathieu, D. L. Sellers, D. Baker, H. Ruohola-Baker

The paper investigates how the valency of F-domain scaffolds affects signaling through the angiopoietin pathway, finding that higher valency mimics Ang1's pro-angiogenic effects while lower valency mimics Ang2's antagonistic effects.

bioRxiv · Sep 19, 2020Biochemistry

The C. elegans RIG-I homolog drh-1 mediates the Intracellular Pathogen Response upon viral infection

J. N. Sowa, H. Jiang, L. Somasundaram, G. Xu, D. Wang, E. Troemel

This paper shows that drh-1 in C. elegans mediates the Intracellular Pathogen Response (IPR) to viral infection, acting as a pattern-recognition receptor independent of its role in RNAi.

bioRxiv · Jul 18, 2019Microbiology