Author
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2 papers
Recent·Most cited
R. Y. Chow, T. M. Levee, G. Kaur, D. P. Cedeno, L. T. Doan, S. X. Atwood
The paper identifies MTOR as a driver of basal cell carcinoma growth by activating aPKC, showing that MTOR inhibition reduces tumor growth in mouse models.
Experimental Dermatology · Mar 1, 2021Peer-reviewedCancer Biology
T. T. Nguyen, K. Wong, U. S. Jeon, V. Jhumkhawala, D. Luy, K. C. Tan, I. Wickramatunga, V. Kumar, W. E. England, L. T. Doan, R. C. Spitale, S. X. Atwood
The paper shows that aPKC isoforms sustain HH signaling and BCC growth without primary cilia by compensating for ciliary loss in advanced cancers.
bioRxiv · Jun 8, 2020 · PreprintCancer Biology