An in vitro method for inducing titan cells reveals novel features of yeast-to-titan switching in the human fungal pathogen Cryptococcus gattii
R. C. May, L. Saidykhan, J. Correia, A. Romanyuk, G. E. Desanti, L. Taylor-Smith, M. Makarova, E. R. Ballou
This paper develops an in vitro method to induce titan cells in Cryptococcus gattii and identifies p-Aminobenzoic acid as a key inducer, revealing strain-specific differences and asynchronous cell cycle features during titanisation.
bioRxiv · Feb 1, 2022Microbiology