Author

D. M. MacCallum

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:fungi (other)· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2

Frequent Co-Authors

C. A. Munro· 3 shared A. Chapuis· 2 shared E. R. Ballou· 2 shared I. M. Dambuza· 2 shared A. Bojarczuk· 1 shared A. Scheynius· 1 shared C. Gourlay· 1 shared D. Corzo-Leon· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersMicrobiology

C. A. Munro

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Author profile →

5 papers

Recent·Most cited

Malassezia sympodialis Mala s 1 allergen is a potential KELCH protein that cross reacts with human skin

D. E. Corzo-Leon, A. Scheynius, D. M. MacCallum, C. A. Munro

This study identifies Mala s 1 as a KELCH-like β-propeller protein in Malassezia sympodialis that cross-reacts with human skin proteins, potentially contributing to immune responses in skin diseases.

bioRxiv · Nov 2, 2022 · PreprintImmunology

Host responses in an ex-vivo human skin model challenged with Malassezia sympodialis

D. Corzo-Leon, D. M. MacCallum, C. A. Munro

This study examines host responses to Malassezia sympodialis in ex-vivo human skin models with and without oleic acid, finding differential gene expression and cytokine levels.

bioRxiv · Jul 22, 2020Microbiology

Host environmental conditions induce small fungal cell size and alter population heterogeneity in Cryptococcus neoformans

X. Zhou, H. Zafar, P. C. S. Sephton-Clark, S. H. Mohamed, A. Chapuis, M. Makarova, D. M. MacCallum, R. Drummond, I. M. Dambuza, E. R. Ballou

The paper investigates the relationship between titan cells, small cells, and titanides in Cryptococcus neoformans, showing their shared features and impact on aneuploidy and drug resistance.

bioRxiv · Jan 3, 2020 · PreprintMicrobiology

Inhibition of classical and alternative modes of respiration in C. albicans leads to cell wall remodelling and increased macrophage recognition

L. Duvenage, L. A. Walker, A. Bojarczuk, S. A. Johnston, D. M. MacCallum, C. A. Munro, C. Gourlay

This paper inhibits respiration in C. albicans using low-toxicity chemicals, leading to cell wall changes and increased macrophage recognition, but also enhancing virulence.

bioRxiv · May 24, 2018Microbiology

The Cryptococcus neoformans Titan cell is an inducible and regulated morphotype underlying pathogenesis

I. M. Dambuza, T. Drake, A. Chapuis, L. Taylor-Smith, N. LeGrave, T. Rasmussen, M. C. Fisher, T. Bicanic, T. S. Harrison, M. Jaspars, R. C. May, G. D. Brown, R. Yuecel, D. M. MacCallum, E. R. Ballou

This paper establishes an in vitro system to induce Titan cells in Cryptococcus neoformans, identifies bacterial peptidoglycan as an inducer, and shows that Titanisation is regulated and conserved across species.

bioRxiv · Sep 19, 2017Microbiology