Author

T. Bicanic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:fungi (other)· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

T. S. Harrison· 2 shared A. Chapuis· 1 shared A. J. P. Brown· 1 shared A. Lewis· 1 shared A. Loyse· 1 shared A. M. Condliffe· 1 shared C. Hollingsworth· 1 shared D. D. Thomson· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersMicrobiology

T. S. Harrison

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Candida spp. suppress neutrophil reactive nitrogen species to evade killing

T. B. Burgess, F. R. Hammond, P. T. Szkuta, A. Lewis, S. Christou, K. A. Bowden, T. Bicanic, L. Prince, K. R. Ayscough, D. G. Partridge, S. A. Johnston, A. M. Condliffe, P. M. Elks

This study shows that Candida spp. suppress neutrophil reactive nitrogen species to evade killing, and restoring RNS via Hif-1 stabilisation improves infection outcomes.

bioRxiv · Nov 2, 2023Immunology

Heightened efficacy of anidulafungin when used in combination with manogepix or 5-flucytosine against Candida auris in vitro

L. L. H. John, D. D. Thomson, T. Bicanic, M. Hönigl, A. J. P. Brown, T. Harrison, E. Bignell

This study shows that combining anidulafungin with manogepix or 5-flucytosine enhances antifungal efficacy against Candida auris in vitro.

bioRxiv · Dec 16, 2022 · PreprintMicrobiology

Transcriptional Profiling of Patient Isolates Identifies a Novel TOR Regulatory Pathway in Cryptococcal Virulence

Y.-D. Park, J. N. Jarvis, G. Hu, S. E. Davis, J. Qiu, N. Zhang, C. Hollingsworth, A. Loyse, P. J. Gardina, T. Valyi-Nagy, T. G. Myers, T. S. Harrison, T. Bicanic, P. R. Williamson

The paper identifies a novel TOR-regulated pathway involving STL1 that enhances Cryptococcus virulence in low-nutrient conditions.

bioRxiv · Jul 13, 2018Microbiology

The Cryptococcus neoformans Titan cell is an inducible and regulated morphotype underlying pathogenesis

I. M. Dambuza, T. Drake, A. Chapuis, L. Taylor-Smith, N. LeGrave, T. Rasmussen, M. C. Fisher, T. Bicanic, T. S. Harrison, M. Jaspars, R. C. May, G. D. Brown, R. Yuecel, D. M. MacCallum, E. R. Ballou

This paper establishes an in vitro system to induce Titan cells in Cryptococcus neoformans, identifies bacterial peptidoglycan as an inducer, and shows that Titanisation is regulated and conserved across species.

bioRxiv · Sep 19, 2017Microbiology