Author

L. Van Aelst

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Eberhardt· 1 shared A. Pommier· 1 shared A. S. Almeida· 1 shared B. Alagesan· 1 shared C. O. dos Santos· 1 shared D. A. Tuveson· 1 shared D. J. Pappin· 1 shared D. K. Cheng· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Eberhardt

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2 papers

Recent·Most cited

Oncogenic KRAS engages an RSK1/NF1 complex in pancreatic cancer

D. K. Cheng, T. E. Oni, Y. Park, J. S. Thalappillil, H.-c. Ting, N. Prasad, B. Alagesan, K. D. Rivera, D. J. Pappin, L. Van Aelst, D. A. Tuveson

This study identifies RSK1 as a KRASG12D-specific interactor in PDAC and shows RSK1 mediates negative feedback on wild-type KRAS.

bioRxiv · Sep 14, 2020 · PreprintCancer Biology

Cancer cell CCR2 orchestrates suppression of the adaptive immune response

M. R. Fein, X. Y. He, A. S. Almeida, E. Bruzas, A. Pommier, R. Yan, A. Eberhardt, D. T. Fearon, L. Van Aelst, J. E. Wilkinson, C. O. dos Santos, M. Egeblad

This study shows that CCR2 in cancer cells suppresses immune response by reducing CD103+ dendritic cell recruitment and altering immune cell infiltration and activation.

bioRxiv · Dec 27, 2019Cancer Biology