Author

W. Roos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:protein folding & dynamics· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Organism:human· 1

Frequent Co-Authors

G. wuite· 2 shared N. De Franceschi· 2 shared P. Bassereau· 2 shared S. Maity· 2 shared W. Weissenhorn· 2 shared A. Desfosses· 1 shared C. Boscheron· 1 shared D. Guilligay· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

G. wuite

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Structural basis of CHMP2A-CHMP3 ESCRT-III polymer assembly and membrane cleavage

K. Azad, D. Guilligay, C. Boscheron, S. Maity, N. De Franceschi, G. Sulbaran, G. Effantin, H. Wang, J.-P. Kleman, P. Bassereau, G. Schoehn, W. Roos, A. Desfosses, W. Weissenhorn

This study presents cryo-EM structures of CHMP2A-CHMP3 ESCRT-III filaments and shows they constrict and cleave membrane tubes through electrostatic interactions and VPS4-mediated remodeling.

bioRxiv · Apr 12, 2022Cell Biology

Control of septum thickness by a large protein ring

M. Wenzel, I. Celik Gulsoy, Y. Gao, J. Willemse, M. G. M. van Rosmalen, G. wuite, W. Roos, L. W. Hamoen

This study shows that SepF protein rings in bacteria control septal thickness, with ring diameter correlating to septum thickness and manipulation of ring size altering septum thickness.

bioRxiv · Feb 11, 2020 · PreprintMicrobiology

The ESCRT-III Isoforms CHMP2A And CHMP2B Display Different Effects On Membranes Upon Polymerization

M. Alqabandi, N. de Franceschi, N. Miguet, S. Maity, M. Bally, W. Roos, W. Weissenhorn, P. Bassereau, S. Mangenot

This study compares the membrane interactions of CHMP2A and CHMP2B, finding they have distinct lipid binding preferences and mechanical effects on membranes.

bioRxiv · Sep 3, 2019Biophysics

The fluid membrane determines mechanics of red blood cell extracellular vesicles and is softened in hereditary spherocytosis

D. Vorselen, S. van Dommelen, R. Sorkin, J. Schiller, R. van Wijk, R. Schiffelers, G. Wuite, W. Roos

This study uses atomic force microscopy to analyze the mechanical properties of red blood cell extracellular vesicles from healthy individuals and a hereditary spherocytosis patient, finding that vesicles have a lower bending modulus in the disease state.

bioRxiv · Nov 1, 2017Biophysics