Author

L.-C. Huang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

A. C. Newton· 1 shared A. P. Kornev· 1 shared A. Venkat· 1 shared C. A. Pilo· 1 shared C. Longman· 1 shared D. J. Gonzalez· 1 shared D. P. Byrne· 1 shared D.-H. Chen· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

A. C. Newton

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Author profile →

2 papers

Recent·Most cited

Protein Kinase C gamma Mutations Drive Spinocerebellar Ataxia Type 14 by Impairing Autoinhibition

C. A. Pilo, T. R. Baffi, A. P. Kornev, M. T. Kunkel, M. Malfavon, D.-H. Chen, L.-C. Huang, C. Longman, N. A. Kannan, W. H. Raskind, D. J. Gonzalez, S. S. Taylor, G. Gorrie, A. C. Newton

SCA14 driver mutations in PKCγ impair autoinhibition, with defect correlating inversely with age of disease onset.

bioRxiv · Jun 24, 2021 · PreprintBiochemistry

KinOrtho: a method for mapping human kinase orthologs across the tree of life and illuminating understudied kinases

L.-C. Huang, R. Taujale, N. Gravel, A. Venkat, W. Yeung, D. P. Byrne, P. A. Eyers, N. Kannan

KinOrtho maps human kinase orthologs across 17,000 species, identifies understudied kinases, and proposes their functions using domain-based approaches and machine learning.

bioRxiv · Mar 5, 2021Evolutionary Biology