Author

L.-M. Appel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

D. Slade· 3 shared A. Akalin· 2 shared I. Grishkovskaya· 2 shared K. Djinovic-Carugo· 2 shared V. Franke· 2 shared A. Kasiliauskaite· 1 shared A. Neudolt· 1 shared A. Peaucelle· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBiochemistry

D. Slade

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Imaging the microscopic viscoelastic anisotropy in living cells

H. Keshmiri, D. Cikes, M. Samalova, L. Schindler, L.-M. Appel, M. Urbanek, I. Yudushkin, D. Slade, W. J. Weninger, A. Peaucelle, J. Penninger, K. Elsayad

This paper introduces BLAM, a technique to map high-frequency viscoelastic anisotropy in living cells, and applies it to study plant cell wall growth and mammalian nuclear mechanics.

bioRxiv · May 28, 2023 · PreprintBiophysics

The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators

L.-M. Appel, I. Grishkovskaya, J. Benedum, V. Franke, A. Polyansky, A. Neudolt, A. Wunder, B. Zagrovic, A. Akalin, K. Djinovic-Carugo, D. Slade

bioRxiv · Feb 26, 2022 · PreprintBiochemistry

PHF3 regulates neuronal gene expression through the new Pol II CTD reader domain SPOC

L.-M. Appel, V. Franke, M. Bruno, I. Grishkovskaya, A. Kasiliauskaite, U. E. Schoeberl, M. G. Puchinger, S. Kostrhon, E. Beltzung, K. Mechtler, G. Lin, A. Vlasova, M. Leeb, R. Pavri, A. Stark, , D. Slade

This study identifies PHF3 as a CTD-binding factor that regulates neuronal gene expression by inhibiting Pol II elongation and mRNA stability.

bioRxiv · Feb 11, 2020Biochemistry