Yuguang J. Ban

MicroRNA-29a enhances and preserves stem-like CD8 T cell differentiation by regulating master epigenetic circuits of exhaustion.

This study shows miR-29a reprograms exhausted CD8 T cells into a stem-like state, enhancing their effector function and response to checkpoint inhibitors.

Targeting CREB remodels the immune microenvironment to enhance immunotherapy responses in pancreatic cancer

This study shows that targeting CREB reduces immunosuppression in pancreatic cancer by altering macrophage polarization and enhancing immunotherapy effectiveness.

pathwayPCA: an R package for integrative pathway analysis with modern PCA methodology and gene selection

pathwayPCA is an R package that performs integrative pathway analysis with modern PCA methods and gene selection, enabling multi-omics data analysis and sample-specific pathway activity estimation.

GSKB: A gene set database for pathway analysis in mouse

The paper creates a gene set database for pathway analysis in mouse, enabling pathway analysis and meta-analysis of gene expression signatures.