Phosphoproteomics of cellular mechanosensing reveals NFATC4 as a regulator of myofibroblast activity
Laura F. Mattner, Zhen Zeng, Christoph H. Mayr, Meshal Ansari, Xin Chuan Wei, Sara Asgharpour, Anita A. Wasik, Nikolaus Kneidinger, Mircea-Gabriel Stoleriu, Jürgen Behr, Julien Polleux, Ali Önder Yildirim, Gerald Burgstaller, Matthias Mann, Herbert B. Schiller
This study identifies NFATC4 as a regulator of myofibroblast activity through phosphoproteomic analysis of fibroblast mechanosensing on stiffness-modulated substrates.
bioRxiv · Feb 13, 2023 · PreprintSystems Biology