Herbert B. Schiller

This paper presents the first single-nucleus RNA sequencing atlas of pleuroparenchymal fibroelastosis, identifying novel cell states and their spatial organization in lung fibrosis.

The paper characterizes compartment-specific proteomic changes in liver fibrosis models and identifies potential therapeutic targets.

hadge combines hashing and genotype-based deconvolution methods to recover previously discarded cells in single-cell data.

This study identifies NFATC4 as a regulator of myofibroblast activity through phosphoproteomic analysis of fibroblast mechanosensing on stiffness-modulated substrates.

CellRank maps cell fates in single-cell RNA sequencing data by integrating RNA velocity and trajectory inference, revealing novel regeneration trajectories in lung injury.

This study investigates Fgfr2b signaling's role in alveolar epithelial lineage commitment during mouse lung development and injury repair, identifying key regulatory genes and lineage contributions.

The paper uses single-cell RNA sequencing to map transcriptional trajectories of human pluripotent stem cells differentiating into lung and hepatocyte progenitors, identifying key signaling pathways and alternative developmental paths.

The paper uses single-cell RNA-seq to identify Krt8+ progenitor cells involved in lung regeneration and shows their role in epithelial differentiation and disease.