Author

Laura M. Desrochers

AstraZeneca (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Adolfo AmiciiD· 1 shared Andrea LoretoiD· 1 shared Andrew OsborneiD· 1 shared Bart NieuwenhuisiD· 1 shared Boštjan KobeiD· 1 shared Carlo Angeletti· 1 shared Cécilia LégaréiD· 1 shared Cynthia GagnoniD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Adolfo AmiciORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintOct 1, 2026

Three-Year Longitudinal Analysis of Splicing Changes in Myotonic Dystrophy Type 1

Cécilia Légaré, Lori Planco, Robert Merritt…·Élise Duchesne

This study tracks splicing index changes in DM1 patients over three years, finding worsening SI scores with variability among participants and associations with clinical phenotypes and baseline severity.

DOI 10.64898/2026.09.25.754454

humanbulk RNA-seq

𝕏 PostBluesky

NeuroscienceeLifePeer-reviewedDec 6, 2021

Potent activation of SARM1 by NMN analogue VMN underlies vacor neurotoxicity

Andrea Loreto, Carlo Angeletti, Weixi Gu…·Michael P. Coleman

This study identifies VMN, a metabolite of the pesticide vacor, as a potent SARM1 activator, showing that SARM1 removal rescues vacor-induced neuron and axon death.

70 citations

Drosophilaexperimental assay

𝕏 PostBluesky