Tunable Magnetorheological Elastomer Substrates for Studying Mechano-Genetic Interactions in Hypertrophic Cardiomyopathy
Yasaman Kargar Gaz Kooh, Yuwen Sun, Ganesh Malayath, Leah Hayem, Bahareh Bahmani, Nongmaithem Debeni Devi, Huanzhu Jiang, Feng Long, Sharon Cresci, Guy M. Genin, Nathaniel Huebsch
This study uses tunable magnetorheological elastomer substrates to investigate mechano-genetic interactions in HCM by applying dynamic mechanical stress to hiPSC-derived cardiomyocytes with a MYBPC3 mutation.
bioRxiv · Oct 27, 2026 · PreprintBioengineering