Author

Leah Krotee

Dana-Farber Cancer Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:proteomics· 1

Frequent Co-Authors

Anthony G. LetaiiD· 2 shared Jeremy A. RyaniD· 2 shared Amulya Jakkani· 1 shared Andrew A. LaneiD· 1 shared Antonio J. AlmazaniD· 1 shared Brenda C. Chan· 1 shared Cheyanne Walker-WilliamsiD· 1 shared Christopher R. ReillyiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Anthony G. LetaiORCID

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2 papers

Recent·Most cited

Drug tolerant persisters and immunotherapy persister cells exhibit cross-resistance and share common survival mechanisms

Maria Davern, Cole J. Turner, Daryl Griffin, Lara Bencsics, Brenda C. Chan, Jasmine Yun-Tong Kung, Michael Olson, Cheyanne Walker-Williams, Shaili Soni, Leah Krotee, Michael Yorsz, Gabriella Antonellis, Patrick Hall Lizotte, Cloud Peter Paweletz, Jeremy A. Ryan, , Anthony G. Letai

This study identifies common survival mechanisms between drug-tolerant persisters and immunotherapy persisters, showing they share reduced mitochondrial apoptotic sensitivity and cross-resistance to therapies.

Cell Death and Differentiation · Dec 26, 2025Peer-reviewedCancer Biology

Dynamic BH3 profiling predicts clinical outcomes in acute myeloid leukemia

Emma Minihane, Leah Krotee, Jason H. Y. Wu, Lindsey Thornton, Geoffrey G. Fell, Sonja Herter, Jeremy A. Ryan, Amulya Jakkani, Kate Marinchev, Andrew A. Lane, Marlise Rachael Luskin, Eric S. Winer, Evan Chris Chen, Shai O. Shimony, Martha Wadleigh, , Jacqueline Suen Garcia

This paper uses Dynamic BH3 Profiling to predict clinical outcomes in AML by assessing drug-induced apoptotic priming in patient samples.

bioRxiv · Oct 14, 2025 · PreprintCancer Biology