Ready-to-load MHC-I Nanoparticles for High-throughput T cell Screening Studies
Hoang Anh T. Phan, Soomin Eom, Daniel Hwang, Michael C. Young, Shirley M. Sun, Molly C. Erdman, Yi Sun, Leena Mallik, Photis Rotsides, Mark M. Painter, E. John Wherry, Dimitri S. Monos, Nikolaos G. Sgourakis
The paper introduces VLP-Open HLA nanoparticles for high-throughput T cell screening, enabling efficient peptide exchange and antigen-specific T cell activation.
Science Advances · Jun 12, 2026Peer-reviewedImmunology